Bioinformatics Infrastr​​uct​ure Facility for Promotion of Biology Teaching​


Objectives
Bioinformatics Infrastructure Facility (BIF) sponsored by Sponsored by Department of Biotechnology, Bioinformatics Division, Ministry of Science & Technology, Govt of India was established in 2006 with the following objectives:

  • To establish BIF to support the teaching activities of Biology and its allied areas of the host institute in particular and the neighboring institutions in general.
  • To build up information resources, prepare databases of interest to its users and to develop relevant information handling tools and techniques.
  • To access information requirements, organize creation of necessary infrastructure and to provide information and computer support services to the users.
  • To establish linkages with BTISnet of DBT for sharing information Resources and users.
  • To organize Training/Workshops for familiarizing the applications of Bioinformatics in Biology teaching and learning activities.

Infrastructure
The facility has 1 Windows server system, 1 Linux server system, 10 desktop systems, network printer, scanner, copier and LCD projector. 
Bioinformatics softwares and tools available include 

  • Geneious Pro
  • Modeller 9V2
  • MEGA 4.1
  • PHYTHON 2.5
  • Arguslab
  • SYSTAT 12
  • FlexX 4.0
  • Amber 11.0
  • Dock 6.0
  • Autodock and Autodock VINA
  • HADDOCK and MATLAB with bioinformatics toolbox
  • Fuzzylogic toolbox
  • Simbiology.


Research Activities

  • A database on ‘Airborne fungal allergens in indoor environment’ has been prepared and launched. http://www.mscwbif.org/afad
  • Comparative Evolutionary analysis of Fungi found in Lampitomauritii burrow wall.
  • Phylogenetic Analysis of the Fungi isolated from Lampitomauritii burrow wall with references to enzymes Amylase and cellulase.
  • Insilico Analysis of potent bioactive compound targeting fungal pathogenic proteins.
  • Structure prediction of Airborne fungal allergic proteins.
  • Structure comparison studies on Fungal allergic proteins ofAlternariaAlternata
  • M.Phil dissertation- An assessment of airborne fungal allergens in indoor environment: A bioinformatics approach.

Completed Projects

  • A database on ‘Airborne fungal allergens in indoor environment’ has been prepared and launched (http://www.mscwbif.org/afad/).
  • Comparative Evolutionary analysis of Fungi found in Lampitomauritii burrow wall.
  • Phylogenetic Analysis of the Fungi isolated from Lampitomauritii burrow wall with references to enzymes Amylase and cellulase.
  • Insilico Analysis of potent bioactive compound targeting fungal pathogenic proteins.
  • Modeling and Structure comparison of airborne fungal allergic proteins.
  • Influence of the Structure Patterns in the allergic effects of Airborne Fungal allergic proteins of Alternariaalternata- A Structure Comparison Study.
  • Database on Indian Earthworms with Genome and DNA barcoding aspects and available in web.
  • Database on Antifungal plant compounds is completed and available in web.
  • Promoter prediction and comparison of eight strains of Salmonella enterica.
  • Identification of potent Antifungal plant compound against alkaline serine protease of    A. fumigatus by screening and docking was completed and accepted for publication.
  • Phylogenetic Analysis on Metalloproteinases of Aspergillus fumigatus with various fungal Species- AnInsilico Study.
  • Identification of potent Inhibitor for RNA dependent RNA polymerase (RDRP) of Dengue Virus serotype-3- A Molecular docking study.

 

Database
AFAD Database: Screenshots
Database Mainpage:

Search Results 

Publications
ArunJyothi Mathias, Pavitra K B, Manjunath K. 2012. Phylogenetic analysis of airborne fungal allergens using Bioinformatic tools. IJCIB Vol 5(1):1 – 11.

PAPERS PRESENTED

  • ArunJyothi Mathias, Rajshekaran, Manjunath K. The Airborne Fungal Allergens Database: A Collection of Protein sequences  International conference on open source for computer aided drug discovery     organized by IMTECH, Chandigarh from March 22-26, 2009
  • Naveen, Pavithra K B, KavithaB.Presented paper entitled “InSilico Analysis of Potent Bioactive compounds targeting Allergic fungal proteins” (Won First Prize) in two days National Seminar held at Bannari Amman Institute of Technology, Sathyamangalam, TamilNadu.
  • Amruthalakshmi, Pavithra K B, Kavitha B. Presented paper entitled “Comparative Evolutionary analysis of fungi isolated from lampitomauritii burrow wall”  in two days National Seminar held at Bannari Amman Institute of Technology, Sathyamangalam, TamilNadu
  • Pavithra K B and ArunJyothi Mathias. Presented poster entitled “Structure prediction and comparison of airborne fungal allergic proteins of Alternariaalternata” in the symposium “25 years of Bioinformatics in India” Organized by Bioinformatics Center, Pondicherry University on 2nd February2011.
  • Subramaniam, Prabha R, Pavitra K B, Kavitha B. A poster entitled “Promoter prediction and genome comparison of six strains of salmonella enterica” has been presented in one day national seminar ‘Motif’ conducted in BharathiarUniveristy on 19th October 2012.
  • Pavitra K B.,Ithiyaraja M, Kavitha BA paper entitled “Identification of potent antifungal plant compound against alkaline proteinase of Aspergillus fumigatus by Molecular docking” has been presented in Two days National conference conducted by Maharani lakshmiAmmanni College for Women, Bangalore on 23rd and 24th November 2012.
  • Ithiyaraja M, Pavitra K B., Kavitha B. A poster entitled “Phylogenetic analysis on metalloproteinases of Aspergillus fumigatus with various fungal species- An Insilico study” has been presented in Two days National conference conducted by Maharani lakshmiAmmanni College for Women, Bangalore on 23rd and 24th November 2012.

Training Activities


Date

Training program

Participants

No. of users  trained

10-05-2007

Workshop on 'Basics of Bioinformatics'

students

20

17-05-2007

Workshop on 'Basics of Bioinformatics'

Teachers

20

18 - 19 of April 2007

Workshop on 'Basics of Bioinformatics'

students

20

23 - 24 of April 2007

Workshop on 'Basics of Bioinformatics'

students

14

September-October 2007

Workshop on 'Basics of Bioinformatics'

students

21+21 
(2 batches)

12 - 13 of February 2008

Workshop on 'Basics of Bioinformatics'

students

14th March - 11th April 2008

Certificate course on Bioinformatics

students

39

14th to 17th October 2008

National Workshop on Techniques in Molecular biology and Bioinformatics-2008

Teachers & Research Scholars

16

30th Sep to 31st Nov 2008

Basic Bioinformatics

Students

33

May-June 2010

Two months course

B.Sc. Students 
(Department of Microbiology)

15

June-July 2010

Two months Certificate course

M.Sc., Students 
(Department of Microbiology and Biotechnology)

16

Aug-Oct 2010

Two months Certificate course

M.Sc., Students 
(Biochemistry students of Maharani's for Women)

12

April-Jun 2010

Training in Bioinformatics techniques.

M.Sc., Students

30

December 2010

Training in Biotechnics& Bioinformatics Skills

M.Sc., Students 
Department of Microbiology, Biotehnology, Zoology, Biochemistry

29

April-May 2012

Two months advanced Bioinformatics certificate course

M.Sc Students Department of Biotechnology and Biochemistry, Govt. Science College

29

June-July 2012

Two months advanced Bioinformatics Certificate Course

M.Sc. Students

16

December 2012

Basic Bioinformatics

M.Sc Students

14

 

Photographs


 

National Workshop on Techniques in Molecular biology and Bioinformatics-2008

 

Certificate course on Bioinformatics 14th March - 11th April 2008

 


One day workshop on MATLAB and SIMULINK